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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers
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Jansen, Iris (Vrije Universiteit Amsterdam) ;
van der Lee, Sven J (Vrije Universiteit Amsterdam) ;
Gomez-Fonseca, Duber (Washington University School of Medicine) ;
De Rojas, Itziar (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Dalmasso, Maria Carolina (Neurosciences and Complex Systems Unit (ENyS). CONICET. Hospital El Cruce. National University A. Jauretche (UNAJ)) ;
Grenier-Boley, Benjamin (Université de Lille) ;
Zettergren, Anna (University of Gothenburg) ;
Mishra, Aniket (Université de Bordeaux) ;
Ali, Muhammad (Washington University School of Medicine) ;
Andrade, Victor (University Hospital Bonn. Medical Faculty) ;
Bellenguez, Céline (Université de Lille) ;
Kleineidam, Luca (German Center for Neurodegenerative Diseases (DZNE)) ;
Küçükali, Fahri (University of Antwerp. Department of Biomedical Sciences) ;
Sung, Ju Sung (Washington University School of Medicine) ;
Tesí, Niccolo (Vrije Universiteit Amsterdam) ;
Vromen, Ellen (Amsterdam Neuroscience. Neurodegeneration) ;
Wightman, Douglas P (Vrije Universiteit Amsterdam) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Alegret, Montserrat (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Alvarez, Ignacio (Fundació per a la Recerca Biomèdica i Social Mútua de Terrassa) ;
Amouyel, Philippe (Université de Lille) ;
Athanasiu, Lavinia (NORMENT Centre. Institute of Clinical Medicine. University of Oslo and Division of Mental Health) ;
Bahrami, Shahram (NORMENT Centre. Institute of Clinical Medicine. University of Oslo and Division of Mental Health) ;
Bailly, Henri (Université Paris Cité) ;
Belbin, Olivia (Institut d'Investigació Biomèdica Sant Pau) ;
Bergh, Sverre (Vestfold Hospital Trust) ;
Bertram, Lars (University of Lübeck) ;
Biessels, Geert Jan (UMC Utrecht Brain Center) ;
Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ;
Blesa, Rafael (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Boland, Anne (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ;
Buerger, K. (Institute for Stroke and Dementia Research (ISD). University Hospital. LMU Munich) ;
Carracedo, Ángel (Fundación Pública Galega de Medicina Xenómica-CIBERER-IDIS) ;
Cervera Carles, Laura (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Chene, Geneviève (Department of Neurology. CHU de Bordeaux) ;
Claassen, Jurgen (Donders Center for Medical Neuroscience) ;
Debette, Stephanie (University School of Medicine) ;
Deleuze, Jean‑Francois (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ;
De Deyn, Peter Paul (University Medical Center Groningen. Department of Neurology and Alzheimer Center Groningen.) ;
Diehl-Schmid, Janine (kbo-Inn-Salzach-Hospital) ;
Djurovic, Srdjan (University of Bergen. Department of Clinical Science. NORMENT Centre.) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Dufouil, Carole (Pôle de Santé Publique) ;
Duron, Emmanuelle (Univerisité Paris-Saclay) ;
Düzel, Emrah (Otto-von-Guericke University Magdeburg. Institute of Cognitive Neurology and Dementia Research) ;
Fladby, Tormod (Akershus University Hospital. Department of Neurology.) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Frölich, Lutz (Medical Faculty Mannheim. Department of Geriatric Psychiatry. Central Institute of Mental Health.) ;
García-González, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Garcia-Martinez, María (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Giegling, Ina (Medical University of Vienna) ;
Goldhardt, Oliver (Technical University of Munich) ;
Gobom, Johan (Sahlgrenska University Hospital (Suècia)) ;
Grimmer, Timo (Technical University of Munich) ;
Haapasalo, Annakaisa (University of Eastern Finland A.I. Virtanen Institute for Molecular Sciences) ;
Hampel, Harald (Neurology Business Group. Eisai Inc) ;
Hanon, Olivier (Service gériatrie. Centre Mémoire de Ressources et Recherches Ile de France-Broca. AP-HP. Hôpital Broca) ;
Hausner, Lucrezia (Central Institute of Mental Health. Department of Geriatric Psychiatry) ;
Heilmann-Heimbach, Stefanie (Institute of Human Genetics. University of Bonn. School of Medicine and University Hospital Bonn) ;
Helisalmi, Seppo (University of Eastern Finland. Institute of Clinical Medicine) ;
Heneka, Michael (German Center for Neurodegenerative Diseases (DZNE)) ;
Hernández, Isabel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Herukka, Sanna‑Kaisa (University of Eastern Finland. Department of Neurology. Institute of Clinical Medicine) ;
Holstege, Henne (Vrije Universiteit Amsterdam. Section Genomics of Neurodegenerative Diseases and Aging) ;
Jarholm, Jonas (Akershus University Hospital. Department of Neurology.) ;
Kern, Silke (Sahlgrenska University Hospital. Psychiatry. Cognition and Old Age Psychiatry Clinic) ;
Knapskog, Anne‑Brita (Oslo University Hospital. Department of Geriatric Medicine) ;
Koivisto, A.M. (Department of Neurology. Helsinki University Hospital) ;
Kornhuber, Johannes (Friedrich-Alexander Universität Erlangen-Nürnberg) ;
Kuulasmaa, Teemu (University of Eastern Finland) ;
Lage, Carmen (University of California) ;
Laske, Christoph (University of Tübingen. Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy.) ;
Leinonen, Ville (Kuopio University Hospita. Department of Neurosurgery.) ;
Lewczuk, Piotr (Medical University of Białystok. Department of Neurodegeneration Diagnostics.) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
López de Munain, Adolfo (University of The Basque Country) ;
López-Garcia, Sara (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Maier, Wolfgang (University Hospital Bonn. Department of Neurodegenerative Diseases and Geriatric Psychiatry) ;
Marquié, Marta (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Mol, Merel O. (Erasmus Medical Centre. Department of Neurology) ;
Montrreal, Laura (Universitat Internacional de Catalunya. Ace Alzheimer Center Barcelona) ;
Moreno, Fermin (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Moreno-Grau, Sonia (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Nicolas, Gael (Normandie Univ. UNIROUEN. Department of Genetics and CNR-MAJ) ;
Nöthen, Markus M. (Institute of Human Genetics. University of Bonn. School of Medicine and University Hospital Bonn) ;
Orellana, Adelina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Pålhaugen, Lene (Akershus University Hospital. Department of Neurology) ;
Papma, Janne M. (Erasmus MC University Medical Center. Department of Neurology and Alzheimer Center Erasmus MC) ;
Pasquier, Florence (Université Lille) ;
Perneczky, Robert (Imperial College London. Ageing Epidemiology Research Unit) ;
Peters, Oliver (German Center for Neurodegenerative Diseases (DZNE)) ;
Pijnenburg, Yolande A.L. (Amsterdam Neuroscience. Neurodegeneration) ;
Popp, Julius (University Hospital of Lausanne. Department of Psychiatry) ;
Posthuma, Danielle (Vrije Universiteit Amsterdam) ;
Pozueta, Ana (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Priller, Josef (Technical University Munich. Department of Psychiatry and Psychotherapy) ;
Puerta, Raquel (Universitat Internacional de Catalunya. Ace Alzheimer Center Barcelona) ;
Quintela, Inés (Grupo de Medicina Xenómica. Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidade de Santiago de Compostela) ;
Ramakers, Inez (Maastricht University. Department of Psychiatry and Neuropsychologie) ;
Rodríguez-Rodríguez, Eloy (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Rujescu, Dan (Medical University of Vienna. Department of Psychiatry and Psychotherapy) ;
Saltvedt, Ingvild (University Hospital of Trondheim. Department of Geriatrics) ;
Sánchez-Juan, Pascual (Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII) ;
Scheltens, Philip (Amsterdam Neuroscience. Neurodegeneration) ;
Scherbaum, Norbert (University of Duisburg-Essen) ;
Schmid, Matthias (University Hospital of Bonn. Institute of Medical Biometry) ;
Schneider, Anja (German Center for Neurodegenerative Diseases (DZNE)) ;
Selbæk, Geir (Oslo University Hospital.Department of Geriatric Medicine) ;
Selnes, Per (Akershus University Hospital. Department of Neurology) ;
Shadrin, Alexey (University of Oslo and Division of Mental Health. Institute of Clinical Medicine) ;
Skoog, Ingmar (Sahlgrenska University Hospital (Suècia)) ;
Soininen, Hilkka (University of Eastern Finland. Institute of Clinical Medicine.) ;
Tárraga, Lluís (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Teipel, Stefan (Rostock University Medical Center. Department of Psychosomatic Medicine) ;
Tijms, Betty M (Amsterdam Neuroscience. Neurodegeneration) ;
Tsolaki, Magda (Aristotle University of Thessaloniki) ;
Van Broeckhoven, Christine (Neurodegenerative Brain Diseases Group. VIB Center for Molecular Neurology. VIB) ;
Van Dongen, Jasper (University of Antwerp. Department of Biomedical Sciences) ;
van Swieten, John C. (Erasmus MC University Medical Center) ;
Vandenberghe, Rik (Leuven Brain Institute. Department of Neurosciences.) ;
Vidal, Jean‑Sébastien (Université Paris Cité) ;
Visser, Pieter J. (Division of Neurogeriatrics Karolinska Institutet. Department of Neurobiology) ;
Vogelgsang, Jonathan (Harvard Medical School. Department of Psychiatry) ;
Waern, Margda (Sahlgrenska University Hospital (Suècia)) ;
Wagner, Michael (German Center for Neurodegenerative Diseases (DZNE)) ;
Wiltfang, Jens W (Medical Science Department. iBiMED) ;
Wittens, Mandy M.J. (Vrije Universiteit Brussel) ;
Zetterberg, Henrik (Hong Kong Center for Neurodegenerative Diseases) ;
Zulaica, Miren (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
van Duijn, Cornelia M. (Nuffield Department of Population Health. Oxford University) ;
Bjerke, Maria (Universitair Ziekenhuis Brussel) ;
Engelborghs, Sebastiaan (Universitair Ziekenhuis Brussel. Department of Neurology) ;
Jessen, Frank (University of Cologne) ;
Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ;
Pastor, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hiltunen, Mikko (University of Eastern Finland. Institute of Biomedicine) ;
Ingelsson, Martin (University of Toronto. Department of Medicine) ;
Andreassen, Ole A (Oslo University Hospital (Oslo, Noruega)) ;
Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sleegers, Kristel (University of Antwerp. Department of Biomedical Sciences) ;
Ruiz, Agustín (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Ramirez, Alfredo (Department of Psychiatry. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases) ;
Cruchaga, Carlos (Washington University School of Medicine. Hope Center for Neurological Disorders) ;
Lambert, Jean-Charles (Institut Pasteur de Lille) ;
van der Flier, Wiesje M (Amsterdam Neuroscience. Neurodegeneration) ;
Universitat Autònoma de Barcelona
Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer's disease (AD) more directly than clinical diagnosis. Initiated by the European Alzheimer & Dementia Biobank (EADB), the largest collaborative effort on genetics underlying CSF biomarkers was established, including 31 cohorts with a total of 13,116 individuals (discovery n = 8074; replication n = 5042 individuals). [...]
2022 -  10.1007/s00401-022-02454-z
Acta Neuropathologica, Vol. 144 Núm. 5 (november 2022) , p. 821-842
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22 p, 3.0 MB |
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
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Vidal Barba, Enric (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Sánchez-Martín, Manuel A. (Universidad de Salamanca. Departamento de Medicina) ;
Eraña, Hasier (Instituto de Salud Carlos III. Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC)) ;
Lázaro, Sonia Pérez (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Pérez-Castro, Miguel A. (Basque Centre for Climate Change (Bilbao)) ;
Otero García, Alicia (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Charco, Jorge M. (Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ;
Marín, Belén (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
López-Moreno, Rafael (Basque Research and Technology Alliance (BRTA). Centro de Investigación Cooperativa en Biociencias) ;
Díaz-Domínguez, Carlos M. (Basque Centre for Climate Change (Bilbao)) ;
Geijo, Maria V (NEIKER-Basque Institute for Agricultural Research and Development) ;
Ordóñez, Montserrat (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
di Bari, Michele (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
Lorenzo, Nuria L. (Universidade de Santiago de Compostela) ;
Pirisinu, Laura (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
d'Agostino, Claudia (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
Torres, Juan María (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Béringue, Vincent (Université Paris-Saclay. Institut National de La Recherche Agronomique) ;
Telling, Glenn (Colorado State University. Prion Research Center and the Department of Microbiology, Immunology, and Pathology) ;
Badiola Díez, Juan José (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Pumarola i Batlle, Martí (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Bolea, Rosa (Universidad de Zaragoza. Centro de Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Nonno, Romolo (Istituto Superiore Di Sanità. Department of Food Safety, Nutrition and Veterinary Public Health) ;
Requena, Jesús R. (Universidade de Santiago de Compostela) ;
Castilla, Joaquín (IKERBASQUE. Basque Foundation for Science)
Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective breeding or other strategies as it is done for classical scrapie outbreaks. [...]
2022 - 10.1186/s40478-022-01477-7
Acta neuropathologica communications, Vol. 10 (december 2022)
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18 p, 2.0 MB |
A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics
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Nicolas, Gaël (Normandie University) ;
Sévigny, Myriam (Laval University) ;
Lecoquierre, François (Normandie University) ;
Marguet, Florent (Normandie University) ;
Deschênes, Andréanne (Laval University) ;
del Pelaez, Maria Carment (Laval University) ;
Feuillette, Sébastien (Normandie University) ;
Audebrand, Anaïs (Laval University) ;
Lecourtois, Magalie (Normandie University) ;
Rousseau, Stéphane (Normandie University) ;
Richard, Anne-Claire (Normandie University) ;
Cassinari, Kévin (Normandie University) ;
Deramecourt, Vincent (University of Lille) ;
Duyckaerts, Charles (Hôpital de la Pitié-Salpêtrière) ;
Boland, Anne (Université Paris-Saclay) ;
Deleuze, Jean-François (Université Paris-Saclay) ;
Meyer, Vincent (Université Paris-Saclay) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Gelpi, Ellen (Medical University of Vienna) ;
Akiyama, Haruhiko (Tokyo Metropolitan Institute of Medical Science) ;
Hasegawa, Masato (Tokyo Metropolitan Institute of Medical Science) ;
Kawakami, Ito (Tokyo Metropolitan Institute of Medical Science) ;
Wong, Tsz H. (Erasmus Medical Center) ;
Van Rooij, Jeroen G. J. (Erasmus Medical Center) ;
Van Swieten, John C. (Erasmus Medical Center) ;
Campion, Dominique (Normandie University) ;
Dutchak, Paul A. (Laval University) ;
Wallon, David (Normandie University) ;
Lavoie-Cardinal, Flavie (Laval University) ;
Laquerrière, Annie (Normandie University) ;
Rovelet-Lecrux, Anne (Normandie University) ;
Sephton, Chantelle F. (Laval University) ;
Universitat Autònoma de Barcelona
Frontotemporal dementia (FTD) is a heterogeneous clinical disorder characterized by progressive abnormalities in behavior, executive functions, personality, language and/or motricity. A neuropathological subtype of FTD, frontotem‑poral lobar degeneration (FTLD)-FET, is characterized by protein aggregates consisting of the RNA-binding protein fused in sarcoma (FUS). [...]
2022 - 10.1186/s40478-022-01314-x
Acta neuropathologica communications, Vol. 10 (february 2022)
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19 p, 6.1 MB |
TREM2 expression in the brain and biological fluids in prion diseases
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Diaz-Lucena, Daniela (Institut d'Investigació Biomèdica de Bellvitge) ;
Kruse, Niels (University Medical Center Göttingen. Institute of Neuropathology) ;
Thüne, Katrin (University Medical Center Göttingen. Department of Neurology) ;
Schmitz, Matthias (German Center for Neurodegenerative Diseases) ;
Villar-Piqué, Anna (Institut d'Investigació Biomèdica de Bellvitge) ;
da Cunha, Jose Eriton Gomes (Universidade Federal de Pernambuco. Keizo Asami Laboratory) ;
Hermann, Peter (University Medical Center Göttingen. Department of Neurology) ;
López-Pérez, Óscar (Institut d'Investigació Biomèdica de Bellvitge) ;
Andrés-Benito, P (Institut d'Investigació Biomèdica de Bellvitge) ;
Ladogana, Anna (Istituto Superiore Di Sanità. Department of Neurosciences) ;
Calero, Miguel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries) ;
Riggert, Joachim (University Medical School. Department of Transfusion Medicine) ;
Pineau, Hailey (University of Alberta. Department of Medicine-Division of Neurology) ;
Sim, Valerie (University of Alberta. Department of Medicine-Division of Neurology) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ;
Blennow, Kaj (Sahlgrenska University Hospital. Clinical Neurochemistry Laboratory) ;
Del Rio, Jose Antonio (Universitat de Barcelona. Institut de Neurociències) ;
Marín-Moreno, Alba (Centro de Investigación en Sanidad Animal. CISA-INIA) ;
Espinosa, Juan Carlos (Centro de Investigación en Sanidad Animal. CISA-INIA) ;
Torres, Juan María (Centro de Investigación en Sanidad Animal. CISA-INIA) ;
Sanchez-Valle, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mollenhauer, Brit (University Medical Centre Göttingen. Department of Neurology) ;
Ferrer, Isidro (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ;
Zerr, Inga (German Center for Neurodegenerative Diseases) ;
Llorens, Franc (University Medical Center Göttingen. Department of Neurology)
Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune cell surface receptor that regulates microglial function and is involved in the pathophysiology of several neurodegenerative diseases. [...]
2021 - 10.1007/s00401-021-02296-1
Acta Neuropathologica, Vol. 141 (april 2021) , p. 841-859
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20 p, 15.9 MB |
Three-dimensional vascular microenvironment landscape in human glioblastoma
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Cribaro, George Paul (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Saavedra-López, Elena (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Romarate, Leire (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Mitxitorena, Izaskun (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Díaz, Laura R. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Casanova, Paola (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Roig-Martínez, Meritxell (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Gallego, José Maria (Hospital General Universitario de Valencia) ;
Perez-Vallés, Ana (Hospital General Universitario de Valencia) ;
Barcia, Carlos (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The cellular complexity of glioblastoma microenvironments is still poorly understood. In-depth, cell-resolution tissue analyses of human material are rare but highly necessary to understand the biology of this deadly tumor. [...]
2021 - 10.1186/s40478-020-01115-0
Acta neuropathologica communications, Vol. 9 (february 2021)
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14 p, 1.2 MB |
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
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van der Lee, Sven J. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ;
Conway, Olivia J. (Mayo Clinic Florida. Department of Neuroscience) ;
Jansen, Iris E (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ;
Carrasquillo, Minerva M. (Mayo Clinic Florida. Department of Neuroscience) ;
Kleineidam, Luca (Uniklinik Köln (Colònia, Alemanya)) ;
van den Akker, Erik (Delft University of Technology. Pattern Recognition and Bioinformatics) ;
Hernández, Isabel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
van Eijk, Kristel R. (University Medical Center Utrecht. Department of Neurology, Brain Center Rudolf Magnus) ;
Stringa, Najada (Vrije Universiteit Amsterdam) ;
Chen, Jason A. (University of California. Interdepartmental Program in Bioinformatics) ;
Zettergren, Anna (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ;
Andlauer, Till F. M. (German Competence Network Multiple Sclerosis (KKNMS)) ;
Diez-Fairen, Monica (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ;
Simon-Sanchez, Javier (University of Tübingen. Hertie Institute for Clinical Brain Research) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ;
Nygaard, Marianne (University of Southern Denmark. The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health) ;
Blauwendraat, Cornelis (National Institute of Neurological Disorders and Stroke. Neurodegenerative Diseases Research Unit) ;
Savage, Jeanne E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ;
Mengel-From, Jonas (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ;
Moreno-Grau, Sonia (Institut Català de Neurociènces Aplicades) ;
Wagner, Michael (DZNE, German Center for Neurodegenerative Diseases) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Keogh, Michael J. (University of Cambridge. Department of Clinical Neurosciences) ;
Blennow, Kaj (Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg. Department of Psychiatry and Neurochemistry) ;
Skoog, Ingmar (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ;
Friese, Manuel A. (Universitätsklinikum Hamburg-Eppendorf. Institut für Neuroimmunologie und Multiple Sklerose (INIMS)) ;
Pletnikova, Olga (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ;
Zulaica, Miren (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Lage, Carmen (IDIVAL) ;
De Rojas, Itziar (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Riedel-Heller, Steffi (University of Leipzig. Institute of Social Medicine, Occupational Health and Public Health (ISAP)) ;
Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Wei, Wei (University of Cambridge. Department of Clinical Neurosciences) ;
Jeune, Bernard (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ;
Orellana, Adelina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Then Bergh, Florian (University of Leipzig. Department of Neurology) ;
Wang, Xue (Mayo Clinic Florida. Department of Neuroscience) ;
Hulsman, Marc (Delft University of Technology. Pattern Recognition and Bioinformatics) ;
Beker, Nina (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Tesi, Niccolo (Delft University of Technology. Pattern Recognition and Bioinformatics) ;
Morris, Christopher M. (Newcastle University. Newcastle Brain Tissue Resource, Edwardson Building, Institute of Neuroscience) ;
Indakoetxea, Begoña (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Collij, Lyduine E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ;
Scherer, Martin (Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center, Hamburg-Eppendorf, Germany) ;
Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ;
Ironside, James W. (University of Edinburgh. Centre for Clinical Brain Sciences) ;
van Berckel, Bart N. M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Wiendl, Heinz (University of Münster. Department of Neurology, Klinik für Neurologie mit Institut für Translationale Neurologie) ;
Strickland, Samantha L. (Mayo Clinic Florida. Department of Neuroscience) ;
Pastor, Pau (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ;
Rodríguez-Rodríguez, Eloy (IDIVAL) ;
Boeve, Bradley (Mayo Clinic Minnesota. Department of Neurology) ;
Petersen, Ronald C. (Mayo Clinic Minnesota. Department of Neurology) ;
Ferman, Tanis J. (Mayo Clinic Florida. Department of Psychiatry and Psychology) ;
van Gerpen, Jay A. (Mayo Clinic Florida. Department of Neurology) ;
Reinders, Marcel J. T. (Delft University of Technology. Delft Bioinformatics Lab) ;
Uitti, Ryan J. (Mayo Clinic Florida. Department of Neurology) ;
Tárraga, Lluís (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Maier, Wolfgang (DZNE, German Center for Neurodegenerative Diseases) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Kawalia, Amit (Uniklinik Köln (Colònia, Alemanya)) ;
Dalmasso, Maria Carolina (Fundación Instituto Leloir (Buenos Aires, Argentina)) ;
Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Zettl, Uwe K. (University of Rostock. Department of Neurology) ;
van Schoor, Natasja M. (Vrije Universiteit Amsterdam) ;
Beekman, Marian (Leiden University Medical Center. Molecular Epidemiology) ;
Allen, Mariet (Mayo Clinic Florida. Department of Neuroscience) ;
Masliah, Eliezer (National Institute on Aging (Estats Units d'Amèrica)) ;
de Munain, Adolfo López (Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ;
Pantelyat, Alexander (Johns Hopkins University Medical Center. Department of Neurology) ;
Wszolek, Zbigniew K. (Mayo Clinic Florida. Department of Neurology) ;
Ross, Owen A. (Mayo Clinic Florida. Department of Neuroscience) ;
Dickson, Dennis W. (Mayo Clinic Florida. Department of Neuroscience) ;
Graff-Radford, Neill R. (Mayo Clinic Florida. Department of Neurology) ;
Knopman, David (Mayo Clinic Minnesota. Department of Neurology) ;
Rademakers, Rosa (Mayo Clinic Florida. Department of Neuroscience) ;
Lemstra, Afina W. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Pijnenburg, Yolande (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Scheltens, Philip (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Gasser, Thomas (University of Tuebingen. Center of Neurology, Department of Neurodegenerative diseases, Hertie-Institute for Clinical Brain Research) ;
Chinnery, Patrick F. (University of Cambridge. MRC Mitochondrial Biology Unit) ;
Hemmer, Bernhard (Munich Cluster for Systems Neurology (SyNergy)) ;
Huisman, Martijn A. (VU University. Department of Sociology) ;
Troncoso, Juan (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ;
Moreno, Fermin (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Nohr, Ellen A. (University of Southern Denmark. Research Unit of Gynecology and Obstetrics, Department of Clinical Research) ;
Sørensen, Thorkild I. A. (Bristol University. MRC Integrative Epidemiology Unit) ;
Heutink, Peter (University of Tübingen. Hertie Institute for Clinical Brain Research) ;
Sánchez-Juan, Pascual (IDIVAL) ;
Posthuma, Danielle (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Christensen, Kaare (Odense University Hospital (Dinamarca)) ;
Ertekin-Taner, Nilüfer (Mayo Clinic Florida. Department of Neurology) ;
Scholz, Sonja (Johns Hopkins University Medical Center. Department of Neurology) ;
Ramirez, Alfredo (Uniklinik Köln (Colònia, Alemanya)) ;
Ruiz, Agustín (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Slagboom, Eline (Dutch Society for Research on Ageing, Leiden, The Netherlands) ;
van der Flier, Wiesje M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Holstege, Henne (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ;
Universitat Autònoma de Barcelona
The genetic variant rs72824905-G (minor allele) in the PLCG2 gene was previously associated with a reduced Alzheimer's disease risk (AD). The role of PLCG2 in immune system signaling suggests it may also protect against other neurodegenerative diseases and possibly associates with longevity. [...]
2019 - 10.1007/s00401-019-02026-8
Acta Neuropathologica, Vol. 138 (may 2019) , p. 237-250
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Correction to : A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
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van der Lee, Sven J. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ;
Conway, Olivia J. (Mayo Clinic Florida. Department of Neuroscience) ;
Jansen, Iris E (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ;
Carrasquillo, Minerva M. (Mayo Clinic Florida. Department of Neuroscience) ;
Kleineidam, Luca (Uniklinik Köln (Colònia, Alemanya)) ;
van den Akker, Erik (Delft University of Technology. Pattern Recognition and Bioinformatics) ;
Hernández, Isabel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
van Eijk, Kristel R. (University Medical Center Utrecht. Department of Neurology, Brain Center Rudolf Magnus) ;
Stringa, Najada (Vrije Universiteit Amsterdam) ;
Chen, Jason A. (University of California. Interdepartmental Program in Bioinformatics) ;
Zettergren, Anna (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ;
Andlauer, Till F. M. (German Competence Network Multiple Sclerosis (KKNMS)) ;
Diez-Fairen, Monica (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ;
Simon-Sanchez, Javier (University of Tübingen. Hertie Institute for Clinical Brain Research) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ;
Nygaard, Marianne (University of Southern Denmark. The Danish Aging Research Center, Epidemiology, Biostatistics and Biodemography, Department of Public Health) ;
Blauwendraat, Cornelis (National Institute of Neurological Disorders and Stroke. Neurodegenerative Diseases Research Unit) ;
Savage, Jeanne E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ;
Mengel-From, Jonas (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ;
Moreno-Grau, Sonia (Institut Català de Neurociènces Aplicades) ;
Wagner, Michael (DZNE, German Center for Neurodegenerative Diseases) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Keogh, Michael J. (University of Cambridge. Department of Clinical Neurosciences) ;
Blennow, Kaj (Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg. Department of Psychiatry and Neurochemistry) ;
Skoog, Ingmar (Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg) ;
Friese, Manuel A. (Universitätsklinikum Hamburg-Eppendorf. Institut für Neuroimmunologie und Multiple Sklerose (INIMS)) ;
Pletnikova, Olga (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ;
Zulaica, Miren (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Lage, Carmen (IDIVAL) ;
De Rojas, Itziar (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Riedel-Heller, Steffi (University of Leipzig. Institute of Social Medicine, Occupational Health and Public Health (ISAP)) ;
Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Wei, Wei (University of Cambridge. Department of Clinical Neurosciences) ;
Jeune, Bernard (University of Southern Denmark. Epidemiology, Biostatistics and Biodemography, Department of Public Health) ;
Orellana, Adelina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Then Bergh, Florian (University of Leipzig. Department of Neurology) ;
Wang, Xue (Mayo Clinic Florida. Department of Neuroscience) ;
Hulsman, Marc (Delft University of Technology. Pattern Recognition and Bioinformatics) ;
Beker, Nina (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Tesi, Niccolo (Delft University of Technology. Pattern Recognition and Bioinformatics) ;
Morris, Christopher M. (Newcastle University. Newcastle Brain Tissue Resource, Edwardson Building, Institute of Neuroscience) ;
Indakoetxea, Begoña (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Collij, Lyduine E. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ;
Scherer, Martin (Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center, Hamburg-Eppendorf, Germany) ;
Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ;
Ironside, James W. (University of Edinburgh. Centre for Clinical Brain Sciences) ;
van Berckel, Bart N. M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Wiendl, Heinz (University of Münster. Department of Neurology, Klinik für Neurologie mit Institut für Translationale Neurologie) ;
Strickland, Samantha L. (Mayo Clinic Florida. Department of Neuroscience) ;
Pastor, Pau (Fundacio per la Recerca Biomedica I Social Mutua Terrassa) ;
Rodríguez-Rodríguez, Eloy (IDIVAL) ;
Boeve, Bradley (Mayo Clinic Minnesota. Department of Neurology) ;
Petersen, Ronald C. (Mayo Clinic Minnesota. Department of Neurology) ;
Ferman, Tanis J. (Mayo Clinic Florida. Department of Psychiatry and Psychology) ;
van Gerpen, Jay A. (Mayo Clinic Florida. Department of Neurology) ;
Reinders, Marcel J. T. (Delft University of Technology. Delft Bioinformatics Lab) ;
Uitti, Ryan J. (Mayo Clinic Florida. Department of Neurology) ;
Tárraga, Lluís (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Maier, Wolfgang (DZNE, German Center for Neurodegenerative Diseases) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Kawalia, Amit (Uniklinik Köln (Colònia, Alemanya)) ;
Dalmasso, Maria Carolina (Fundación Instituto Leloir (Buenos Aires, Argentina)) ;
Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Zettl, Uwe K. (University of Rostock. Department of Neurology) ;
van Schoor, Natasja M. (Vrije Universiteit Amsterdam) ;
Beekman, Marian (Leiden University Medical Center. Molecular Epidemiology) ;
Allen, Mariet (Mayo Clinic Florida. Department of Neuroscience) ;
Masliah, Eliezer (National Institute on Aging (Estats Units d'Amèrica)) ;
de Munain, Adolfo López (Department of Neurology, Hospital Universitario San Sebastian, San Sebastian, Spain) ;
Pantelyat, Alexander (Johns Hopkins University Medical Center. Department of Neurology) ;
Wszolek, Zbigniew K. (Mayo Clinic Florida. Department of Neurology) ;
Ross, Owen A. (Mayo Clinic Florida. Department of Neuroscience) ;
Dickson, Dennis W. (Mayo Clinic Florida. Department of Neuroscience) ;
Graff-Radford, Neill R. (Mayo Clinic Florida. Department of Neurology) ;
Knopman, David (Mayo Clinic Minnesota. Department of Neurology) ;
Rademakers, Rosa (Mayo Clinic Florida. Department of Neuroscience) ;
Lemstra, Afina W. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Pijnenburg, Yolande (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Scheltens, Philip (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Gasser, Thomas (University of Tuebingen. Center of Neurology, Department of Neurodegenerative diseases, Hertie-Institute for Clinical Brain Research) ;
Chinnery, Patrick F. (University of Cambridge. MRC Mitochondrial Biology Unit) ;
Hemmer, Bernhard (Munich Cluster for Systems Neurology (SyNergy)) ;
Huisman, Martijn A. (VU University. Department of Sociology) ;
Troncoso, Juan (Johns Hopkins University Medical Center. Department of Pathology (Neuropathology)) ;
Moreno, Fermin (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Nohr, Ellen A. (University of Southern Denmark. Research Unit of Gynecology and Obstetrics, Department of Clinical Research) ;
Sørensen, Thorkild I. A. (Bristol University. MRC Integrative Epidemiology Unit) ;
Heutink, Peter (University of Tübingen. Hertie Institute for Clinical Brain Research) ;
Sánchez-Juan, Pascual (IDIVAL) ;
Posthuma, Danielle (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Christensen, Kaare (Odense University Hospital (Dinamarca)) ;
Ertekin-Taner, Nilüfer (Mayo Clinic Florida. Department of Neurology) ;
Scholz, Sonja (Johns Hopkins University Medical Center. Department of Neurology) ;
Ramirez, Alfredo (Uniklinik Köln (Colònia, Alemanya)) ;
Ruiz, Agustín (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Slagboom, Eline (Dutch Society for Research on Ageing, Leiden, The Netherlands) ;
van der Flier, Wiesje M. (Vrije Universiteit Amsterdam, Amsterdam UMC. Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience) ;
Holstege, Henne (Vrije Universiteit Amsterdam, Amsterdam UMC. Department of Clinical Genetics) ;
Universitat Autònoma de Barcelona
2020 - 10.1007/s00401-019-02107-8
Acta Neuropathologica, Vol. 139 (january 2020) , p. 959-962
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Lack of pathogenic potential of peripheral α-synuclein aggregates from Parkinson's disease patients
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Recasens, Ariadna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Carballo-Carbajal, Iria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Parent, Annabelle (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bové, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gelpi, Ellen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Tolosa, Eduardo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Vila Bover, Miquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The online version of this article (10. 1186/s40478-018-0509-1) contains supplementary material, which is available to authorized users.
2018 - 10.1186/s40478-018-0509-1
Acta neuropathologica communications, Vol. 6 (february 2018)
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13 p, 1.2 MB |
Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease
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De Roeck, Arne (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Van den Bossche, Tobi (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
van der Zee, Julie (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Verheijen, Jan (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
De Coster, Wouter (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Van Dongen, Jasper (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Dillen, Lubina (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Baradaran-Heravi, Yalda (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Heeman, Bavo (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Sanchez-Valle, Raquel (Hospital Clínic i Provincial de Barcelona) ;
Llado Plarrumani, Albert (Hospital Clínic i Provincial de Barcelona) ;
Nacmias, Benedetta (University of Florence) ;
Sorbi, Sandro (University of Florence) ;
Gelpi, Ellen (Hospital Clínic i Provincial de Barcelona) ;
Grau-Rivera, Oriol (Hospital Clínic i Provincial de Barcelona) ;
Gómez-Tortosa, Estrella (Hospital Universitario Fundación Jiménez Díaz) ;
Pastor, Pau (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Ortega-Cubero, Sara (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Pastor, Maria A. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Graff, Caroline (Karolinska Institutet (Estocolm, Suècia). Center for Alzheimer Research) ;
Thonberg, Håkan (Karolinska Institutet (Estocolm, Suècia). Center for Alzheimer Research) ;
Benussi, Luisa (Istituto Centro San Giovanni di Dio-Fatebenefratelli, Brescia, Italy) ;
Ghidoni, Roberta (Istituto Centro San Giovanni di Dio-Fatebenefratelli, Brescia, Italy) ;
Binetti, Giuliano (Istituto Centro San Giovanni di Dio-Fatebenefratelli, Brescia, Italy) ;
de Mendonça, Alexandre (University of Lisbon, Portugal) ;
Martins, Madalena (University of Lisbon, Portugal) ;
Borroni, Barbara (Centre for Neurodegenerative Disorders, University of Brescia, Italy.) ;
Padovani, Alessandro (Centre for Neurodegenerative Disorders, University of Brescia, Brescia, Italy) ;
Almeida, Maria Rosário (Center for Neuroscience and Cell Biology, University of Coimbra, Portugal) ;
Santana, Isabel (University of Coimbra) ;
Diehl-Schmid, Janine (Technische Universität München) ;
Alexopoulos, Panagiotis (Technische Universität München) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Fortea, Juan (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Tsolaki, Magda (Aristotle University of Thessaloniki) ;
Koutroumani, Maria (Aristotle University of Thessaloniki) ;
Matej, Radoslav (Charles University, Prague, Czech Republic) ;
Rohan, Zdenek (Charles University, Prague, Czech Republic) ;
De Deyn, Peter Paul (Institute Born-Bunge, University of Antwerp, Belgium) ;
Engelborghs, Sebastiaan (Institute Born-Bunge, University of Antwerp, Belgium) ;
Cras, Patrick (Institute Born-Bunge, University of Antwerp, Belgium) ;
Van Broeckhoven, Christine (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Sleegers, Kristel (VIB Center for Molecular Neurology, VIB, Antwerp, Belgium) ;
Universitat Autònoma de Barcelona
Premature termination codon (PTC) mutations in the ATP-Binding Cassette, Sub-Family A, Member 7 gene (ABCA7) have recently been identified as intermediate-to-high penetrant risk factor for late-onset Alzheimer's disease (LOAD). [...]
2017 - 10.1007/s00401-017-1714-x
Acta Neuropathologica, Vol. 134 (april 2017) , p. 475-487
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